产品货号：
Z29769
中文名称：
XAF1抗体
英文名称：
Anti-XAF1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-XAF1 Antibody |
| 指标别名 | XAF1;BIRC4BP;XIAPAF1;BIRC4-binding protein |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | XAF1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | XAF-1 antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human XAF-1.The immunogen is located within the last 50 amino acids of XAF-1. |
| 计算分子量 | 35kDa |
| 成分 | XAF-1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | XAF-1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | XAF-1 binds to XIAP,an inhibitor of caspases-3,-7,and -9,and triggers its relocation from the cytosol to the nucleus.Overexpression of XAF-1 results in the neutralization of XIAP's ability to inhibit cell death.XAF-1 is normally expressed in all adult and fetal tissues but was found to be present in very low levels in a variety of cancer cell lines.In contrast,XIAP levels have been shown to be high in a majority of cell lines.Low XAF-1 and high basal expression of XIAP may therefore play a critical role in maintaining survival of cancer cell lines.Both IFN-alpha2 and IFN-beta can induce XAF-1 mRNA in all cells examined but induction of XAF-1 protein (as observed by immunoblot analysis) was seen only in cell lines sensitive to the apoptotic effects of IFNs. |
| Uniprot ID | Q6GPH4 |
| 基因名全称 | XIAP associated factor 1 |
| 蛋白名全称 | XIAP associated factor 1 |
| 推荐稀释比 | XAF-1 antibody can be used for the detection of XAF-1 by Western blot at 0.5 to 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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